Motif ID: RXR{A,B,G}.p2

Z-value: 1.785


Transcription factors associated with RXR{A,B,G}.p2:

Gene SymbolEntrez IDGene Name
Rxra 20181 retinoid X receptor alpha
Rxrb 20182 retinoid X receptor beta
Rxrg 20183 retinoid X receptor gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrgchr1_+_169528492,
chr1_+_169548381
0.402.8e-08Click!
Rxrbchr17_+_34168703-0.241.3e-03Click!
Rxrachr2_+_275326920.036.9e-01Click!


Activity profile for motif RXR{A,B,G}.p2.

activity profile for motif RXR{A,B,G}.p2


Sorted Z-values histogram for motif RXR{A,B,G}.p2

Sorted Z-values for motif RXR{A,B,G}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXR{A,B,G}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_112910475 24.320 NM_021273
Ckb
creatine kinase, brain
chr17_+_43938789 23.304 NM_207649
Rcan2
regulator of calcineurin 2
chr11_+_101329457 22.434 Rnd2
Rho family GTPase 2
chr10_+_59569052 20.095 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr16_-_85173764 19.837 App
amyloid beta (A4) precursor protein
chr9_+_110148568 19.276 Cspg5
chondroitin sulfate proteoglycan 5
chr13_-_25029458 18.788 NM_172532
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr16_-_85173930 18.750 App
amyloid beta (A4) precursor protein
chr16_-_85173851 18.743 App
amyloid beta (A4) precursor protein
chr16_-_85173918 18.587 App
amyloid beta (A4) precursor protein
chr16_-_85173978 17.790 App
amyloid beta (A4) precursor protein
chr8_+_86496844 17.381 NM_008854
Prkaca
protein kinase, cAMP dependent, catalytic, alpha
chr11_+_78139476 16.962 Aldoc
aldolase C, fructose-bisphosphate
chr2_-_25325248 16.828 NM_008963
Ptgds
prostaglandin D2 synthase (brain)
chr9_-_31019412 16.425 Aplp2
amyloid beta (A4) precursor-like protein 2
chr10_+_59569206 16.354 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr16_-_18629938 15.648 NM_213614
Sept5
septin 5
chr2_-_25325196 15.512 Ptgds
prostaglandin D2 synthase (brain)
chr16_-_84955488 15.177 App
amyloid beta (A4) precursor protein
chr7_-_52124950 13.938 Ptov1
prostate tumor over expressed gene 1
chr2_-_148558110 13.847 NM_019632
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr7_-_52125157 13.687 NM_133949
Ptov1
prostate tumor over expressed gene 1
chr11_+_78136681 13.470 Aldoc
aldolase C, fructose-bisphosphate
chr11_+_101329615 13.358 NM_009708
Rnd2
Rho family GTPase 2
chr13_-_78338131 13.009 NM_010151
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr17_+_43938905 12.929 Rcan2
regulator of calcineurin 2
chr15_-_83936183 12.905 NM_013873
Sult4a1
sulfotransferase family 4A, member 1
chr7_-_149276174 12.595 NM_008748
Dusp8
dual specificity phosphatase 8
chr4_-_151235861 12.526 NM_001081557
NM_001195565
Camta1

calmodulin binding transcription activator 1

chr11_-_115158717 12.466 NM_178035
Fads6
fatty acid desaturase domain family, member 6
chr2_+_164793487 12.328 NM_020333
Slc12a5
solute carrier family 12, member 5
chr9_-_31019234 11.968 Aplp2
amyloid beta (A4) precursor-like protein 2
chr7_-_52622289 11.693 Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr9_-_108363229 11.476 Klhdc8b
kelch domain containing 8B
chr9_-_103132606 11.426 NM_133977
Trf
transferrin
chr8_-_48374715 11.420 Stox2
storkhead box 2
chr8_-_73132125 11.294 NM_133772
Ssbp4
single stranded DNA binding protein 4
chr16_-_85173944 11.098 NM_001198823
NM_001198824
NM_001198825
NM_001198826
NM_007471
App




amyloid beta (A4) precursor protein




chr9_-_103132523 11.040 Trf
transferrin
chr2_+_177876858 10.982 Phactr3
phosphatase and actin regulator 3
chr2_+_164793698 10.949 Slc12a5
solute carrier family 12, member 5
chr18_-_16967754 10.790 Cdh2
cadherin 2
chr7_-_52622373 10.761 NM_029741
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr14_+_64225366 10.402 NM_173393
Xkr6
X Kell blood group precursor related family member 6 homolog
chr9_+_75161942 10.108 NM_138719
Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr19_-_61302538 10.062 Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr11_+_29593657 10.055 NM_194051
Rtn4
reticulon 4
chr11_+_78136690 9.942 Aldoc
aldolase C, fructose-bisphosphate
chr7_+_31092787 9.776 Clip3
CAP-GLY domain containing linker protein 3
chr13_-_78337844 9.719 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr2_+_177876710 9.686 Phactr3
phosphatase and actin regulator 3
chr11_-_69418965 9.644 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr5_-_118694869 9.594 NM_172998
NM_001109902
Rnft2

ring finger protein, transmembrane 2

chr7_-_129245303 9.468 NM_028177
Ndufab1
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1
chr5_+_18732863 9.366 NM_001170746
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_+_76490995 9.351 NM_010630
Kifc2
kinesin family member C2
chr8_-_73011217 9.289 NM_182991
Tmem59l
transmembrane protein 59-like
chr15_+_78744576 9.209 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr2_+_106533281 9.167 Mpped2
metallophosphoesterase domain containing 2
chr5_+_37633317 9.130 NM_001136058
Crmp1
collapsin response mediator protein 1
chr2_+_135885126 9.110 6330527O06Rik
RIKEN cDNA 6330527O06 gene
chr15_+_103333440 9.045 Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr7_+_19661811 9.010 Dmwd
dystrophia myotonica-containing WD repeat motif
chr15_+_78744802 8.947 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr5_+_108797254 8.918 Gm10419
predicted gene 10419
chr7_+_53693190 8.860 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr5_-_31504348 8.846 NM_001177901
Zfp513
zinc finger protein 513
chrX_-_98615096 8.811 NM_001177985
NM_001177986
Zmym3

zinc finger, MYM-type 3

chr15_+_78258993 8.807 NM_001081367
Kctd17
potassium channel tetramerisation domain containing 17
chr10_+_90292453 8.782 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_25886551 8.748 NM_175642
Bai3
brain-specific angiogenesis inhibitor 3
chr17_+_25707771 8.748 2810468N07Rik
RIKEN cDNA 2810468N07 gene
chr8_-_112692071 8.727 NM_007586
Calb2
calbindin 2
chr11_+_71564204 8.705 NM_177618
Wscd1
WSC domain containing 1
chr18_-_16967557 8.666 NM_007664
Cdh2
cadherin 2
chr16_+_41533317 8.615 NM_175548
Lsamp
limbic system-associated membrane protein
chr15_-_83936038 8.548 Sult4a1
sulfotransferase family 4A, member 1
chr5_+_137729501 8.448 NM_009599
Ache
acetylcholinesterase
chr9_+_110147867 8.302 Cspg5
chondroitin sulfate proteoglycan 5
chr15_+_78744328 8.299 NM_020271
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr8_-_48374755 8.182 NM_001114311
Stox2
storkhead box 2
chr15_-_98638230 8.150 Ddn
dendrin
chr2_+_28061156 8.140 NM_001038612
NM_019498
Olfm1

olfactomedin 1

chr17_-_24826812 8.135 Syngr3
synaptogyrin 3
chr1_+_78306890 8.068 NM_001004173
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr3_-_89049756 8.011 NM_183037
Trim46
tripartite motif-containing 46
chr3_+_133903056 7.988 NM_001004367
Cxxc4
CXXC finger 4
chr11_+_69831951 7.978 NM_001109752
NM_007864
Dlg4

discs, large homolog 4 (Drosophila)

chr16_+_5885447 7.960 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr13_-_58009599 7.892 Spock1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
chr11_-_119409041 7.882 NM_008730
Nptx1
neuronal pentraxin 1
chr10_+_90292388 7.874 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_+_60560923 7.820 NM_026235
Larp6
La ribonucleoprotein domain family, member 6
chr5_+_37259906 7.784 Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr18_-_20904585 7.775 NM_019737
B4galt6
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
chr10_-_127058163 7.740 Lrp1
low density lipoprotein receptor-related protein 1
chr3_+_68298129 7.631 Schip1
schwannomin interacting protein 1
chrX_-_149471740 7.631 NM_023788
Mageh1
melanoma antigen, family H, 1
chr9_-_31019392 7.622 NM_001102455
NM_001102456
NM_009691
Aplp2


amyloid beta (A4) precursor-like protein 2


chr6_-_4697009 7.611 NM_001130188
NM_001130189
NM_001130190
NM_001130191
NM_011360
Sgce




sarcoglycan, epsilon




chr17_-_46169322 7.605 NM_001025250
NM_001025257
NM_009505
Vegfa


vascular endothelial growth factor A


chr9_+_75162059 7.603 Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr4_+_137280366 7.602 Rap1gap
Rap1 GTPase-activating protein
chr14_-_55531726 7.597 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr11_+_71564481 7.567 Wscd1
WSC domain containing 1
chr7_-_52622167 7.526 Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr10_+_79167197 7.523 Bsg
basigin
chr11_+_103510822 7.460 NM_001033212
Rprml
reprimo-like
chr4_-_109149038 7.452 NM_013876
Rnf11
ring finger protein 11
chr10_+_79167255 7.389 Bsg
basigin
chr14_+_67530044 7.379 NM_175498
Pnma2
paraneoplastic antigen MA2
chr16_+_18777032 7.343 Cldn5
claudin 5
chr9_-_56483379 7.181 Lingo1
leucine rich repeat and Ig domain containing 1
chr11_-_119903061 7.143 NM_001198787
Aatk
apoptosis-associated tyrosine kinase
chr11_+_92960603 7.107 NM_028296
Car10
carbonic anhydrase 10
chr4_+_124336307 7.053 Pou3f1
POU domain, class 3, transcription factor 1
chr7_+_19868009 7.050 NM_013648
Rtn2
reticulon 2 (Z-band associated protein)
chr2_+_106533615 7.030 NM_001143683
Mpped2
metallophosphoesterase domain containing 2
chr11_+_103510847 6.946 Rprml
reprimo-like
chr2_+_28368766 6.918 Ralgds
ral guanine nucleotide dissociation stimulator
chr16_+_18776955 6.906 Cldn5
claudin 5
chr6_+_113433408 6.874 Creld1
cysteine-rich with EGF-like domains 1
chr12_-_4848240 6.827 NM_016863
Fkbp1b
FK506 binding protein 1b
chr15_-_98638348 6.789 NM_001013741
Ddn
dendrin
chr5_+_34339258 6.751 Nat8l
N-acetyltransferase 8-like
chr11_-_3995299 6.727 NM_026443
Mtfp1
mitochondrial fission process 1
chr17_+_25854116 6.726 NM_022422
Gng13
guanine nucleotide binding protein (G protein), gamma 13
chr10_+_79167102 6.687 NM_001077184
NM_009768
Bsg

basigin

chr1_+_137043277 6.676 NM_026823
Arl8a
ADP-ribosylation factor-like 8A
chr8_-_4259126 6.670 NM_183315
Ctxn1
cortexin 1
chr11_-_116515361 6.630 Cygb
cytoglobin
chr11_+_69832336 6.602 Dlg4
discs, large homolog 4 (Drosophila)
chr2_+_58998938 6.590 Pkp4
plakophilin 4
chrX_-_98615554 6.507 NM_001177988
NM_019831
Zmym3

zinc finger, MYM-type 3

chr6_+_17257720 6.489 Cav1
caveolin 1, caveolae protein
chr19_+_10525829 6.484


chr3_+_117278559 6.479 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr3_+_117278144 6.473 NM_029425
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr11_-_5965555 6.469 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chr19_-_4906607 6.454 NM_001033128
Bbs1
Bardet-Biedl syndrome 1 (human)
chr18_+_37906668 6.428 Pcdhga10
protocadherin gamma subfamily A, 10
chr19_-_7280741 6.425 NM_134150
Otub1
OTU domain, ubiquitin aldehyde binding 1
chr5_-_31504258 6.390 Zfp513
zinc finger protein 513
chr7_+_5031809 6.360 NM_010147
Epn1
epsin 1
chr12_-_73509537 6.319 Rtn1
reticulon 1
chr17_-_24826873 6.249 NM_011522
Syngr3
synaptogyrin 3
chr15_+_78744862 6.241 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr11_+_101017197 6.225 NM_134028
Tubg2
tubulin, gamma 2
chr3_-_152003317 6.210 NM_001162375
NM_174868
Fam73a

family with sequence similarity 73, member A

chr1_+_75542840 6.171 NM_009208
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr2_+_58999028 6.163 Pkp4
plakophilin 4
chr12_+_112997057 6.159 NM_001025360
NM_001081959
NM_008450
Klc1


kinesin light chain 1


chr7_+_133968166 6.130 NM_001146347
Fam57b
family with sequence similarity 57, member B
chr3_+_107698740 6.118 NM_010360
Gstm5
glutathione S-transferase, mu 5
chr4_+_43455122 6.110 NM_011571
Tesk1
testis specific protein kinase 1
chr4_-_75779379 6.071 NM_001014288
Ptprd
protein tyrosine phosphatase, receptor type, D
chr16_+_35155621 6.052 NM_001012765
Adcy5
adenylate cyclase 5
chr15_+_81767370 6.037 Csdc2
cold shock domain containing C2, RNA binding
chrX_-_119510890 6.024 NM_138742
Nap1l3
nucleosome assembly protein 1-like 3
chr17_-_46162111 6.024 NM_001110266
NM_001110267
NM_001110268
Vegfa


vascular endothelial growth factor A


chr15_+_103333554 5.998 NM_008800
Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr11_+_78002309 5.998 Rab34
RAB34, member of RAS oncogene family
chr1_+_74331503 5.993 NM_001039509
NM_025580
Pnkd

paroxysmal nonkinesiogenic dyskinesia

chr8_+_41393330 5.991 NM_030110
Efha2
EF-hand domain family, member A2
chr5_+_37633353 5.978 Crmp1
collapsin response mediator protein 1
chr11_-_116515602 5.950 NM_030206
Cygb
cytoglobin
chr2_+_164793796 5.882 Slc12a5
solute carrier family 12, member 5
chr7_+_4642529 5.877 NM_001003920
NM_001168572
Brsk1

BR serine/threonine kinase 1

chr11_+_102622745 5.864 NM_001110778
NM_009613
Adam11

a disintegrin and metallopeptidase domain 11

chr5_-_31597792 5.853 NM_022424
Fndc4
fibronectin type III domain containing 4
chr19_+_5689759 5.823 Map3k11
mitogen-activated protein kinase kinase kinase 11
chr15_-_58654964 5.772 NM_175212
Tmem65
transmembrane protein 65
chr1_+_60466462 5.744 NM_001198570
NM_001198571
NM_198127
Abi2


abl-interactor 2


chr3_-_57651409 5.696 Pfn2
profilin 2
chrX_+_130829929 5.641 Tmem35
transmembrane protein 35
chr8_+_96334879 5.633 Gnao1
guanine nucleotide binding protein, alpha O
chr11_-_97914582 5.624 NM_146028
Stac2
SH3 and cysteine rich domain 2
chr7_-_31911754 5.577 Scn1b
sodium channel, voltage-gated, type I, beta
chr4_-_57002965 5.560 6430704M03Rik
RIKEN cDNA 6430704M03 gene
chr19_+_53385022 5.550 Mxi1
Max interacting protein 1
chr18_+_38456364 5.519 NM_001164621
Rnf14
ring finger protein 14
chr12_-_73509668 5.512 Rtn1
reticulon 1
chr5_+_34339351 5.511 Nat8l
N-acetyltransferase 8-like
chr4_+_43394824 5.486 NM_001037709
Rusc2
RUN and SH3 domain containing 2
chr19_-_37281951 5.482 Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr18_+_37303622 5.466 NM_001003672
Pcdhac2
protocadherin alpha subfamily C, 2
chr4_-_148473897 5.420 NM_019781
Pex14
peroxisomal biogenesis factor 14
chr18_+_37906739 5.349 NM_033593
Pcdhga10
protocadherin gamma subfamily A, 10
chr4_-_133053867 5.347 Trnp1
TMF1-regulated nuclear protein 1
chr11_-_118770859 5.345 Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr1_+_60466499 5.341 Abi2
abl-interactor 2
chr19_+_8994860 5.332 NM_024256
B3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr6_-_124915441 5.324 Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr17_-_27957398 5.323 NM_001033279
NM_001044719
D17Wsu92e

DNA segment, Chr 17, Wayne State University 92, expressed

chr4_-_133054355 5.321 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr13_-_49243351 5.316 NM_029361
Wnk2
WNK lysine deficient protein kinase 2
chr4_+_43394949 5.306 Rusc2
RUN and SH3 domain containing 2
chr1_+_60466568 5.277 Abi2
abl-interactor 2
chr5_-_31504605 5.259 NM_175311
Zfp513
zinc finger protein 513
chr12_+_3365102 5.233 NM_008445
Kif3c
kinesin family member 3C

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.45 2.85e-10 GO:0051179 localization
1.48 2.50e-09 GO:0051234 establishment of localization
1.48 4.46e-09 GO:0006810 transport
1.69 3.42e-07 GO:0007399 nervous system development
1.77 1.08e-05 GO:0022008 neurogenesis
2.25 1.57e-05 GO:0019226 transmission of nerve impulse
2.25 1.57e-05 GO:0035637 multicellular organismal signaling
1.78 2.02e-05 GO:0048699 generation of neurons
1.55 2.09e-05 GO:0023051 regulation of signaling
2.10 2.73e-05 GO:0044057 regulation of system process
1.53 3.42e-05 GO:0051239 regulation of multicellular organismal process
2.01 8.30e-05 GO:0055082 cellular chemical homeostasis
2.00 1.57e-04 GO:0006873 cellular ion homeostasis
1.92 2.36e-04 GO:0030030 cell projection organization
2.29 2.49e-04 GO:0007268 synaptic transmission
1.60 2.87e-04 GO:0035556 intracellular signal transduction
3.12 3.47e-04 GO:0022900 electron transport chain
2.24 3.81e-04 GO:0007264 small GTPase mediated signal transduction
1.86 3.84e-04 GO:0019725 cellular homeostasis
1.44 4.09e-04 GO:0065008 regulation of biological quality
2.42 5.30e-04 GO:0051969 regulation of transmission of nerve impulse
1.79 5.93e-04 GO:0048878 chemical homeostasis
2.48 6.00e-04 GO:0050804 regulation of synaptic transmission
2.34 6.69e-04 GO:0031644 regulation of neurological system process
1.88 9.43e-04 GO:0050801 ion homeostasis
1.31 2.50e-03 GO:0016043 cellular component organization
1.55 3.00e-03 GO:0032879 regulation of localization
2.01 4.09e-03 GO:0031175 neuron projection development
5.44 4.19e-03 GO:0035249 synaptic transmission, glutamatergic
1.36 4.96e-03 GO:0071842 cellular component organization at cellular level
1.88 5.29e-03 GO:0048666 neuron development
1.27 6.25e-03 GO:0032502 developmental process
1.68 6.77e-03 GO:0007154 cell communication
1.59 7.13e-03 GO:0048468 cell development
2.24 7.37e-03 GO:0071495 cellular response to endogenous stimulus
1.32 8.98e-03 GO:0048731 system development
1.30 9.09e-03 GO:0048856 anatomical structure development
3.21 1.06e-02 GO:0001505 regulation of neurotransmitter levels
1.28 1.10e-02 GO:0007275 multicellular organismal development
1.74 1.11e-02 GO:0030182 neuron differentiation
1.55 1.54e-02 GO:0042592 homeostatic process
1.58 1.60e-02 GO:0016310 phosphorylation
1.49 1.92e-02 GO:0010646 regulation of cell communication
5.78 2.07e-02 GO:0042133 neurotransmitter metabolic process
1.90 2.18e-02 GO:0022603 regulation of anatomical structure morphogenesis
4.71 2.21e-02 GO:0022904 respiratory electron transport chain
1.27 2.27e-02 GO:0071840 cellular component organization or biogenesis
5.14 2.31e-02 GO:0007215 glutamate signaling pathway
6.42 2.56e-02 GO:0007416 synapse assembly
1.54 2.94e-02 GO:2000026 regulation of multicellular organismal development
2.10 3.35e-02 GO:0006091 generation of precursor metabolites and energy
1.33 3.44e-02 GO:0048869 cellular developmental process
1.34 3.48e-02 GO:0030154 cell differentiation
1.79 3.68e-02 GO:0009719 response to endogenous stimulus
1.45 3.72e-02 GO:0050790 regulation of catalytic activity
2.69 4.17e-02 GO:0071375 cellular response to peptide hormone stimulus
1.39 4.20e-02 GO:0065009 regulation of molecular function
3.44 4.42e-02 GO:0050808 synapse organization
1.55 4.54e-02 GO:0006811 ion transport

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.36 1.83e-27 GO:0005737 cytoplasm
1.44 1.39e-22 GO:0044444 cytoplasmic part
1.24 1.44e-21 GO:0005622 intracellular
1.23 1.50e-19 GO:0044424 intracellular part
2.48 1.10e-13 GO:0045202 synapse
1.11 4.24e-12 GO:0005623 cell
1.11 4.24e-12 GO:0044464 cell part
1.21 2.14e-11 GO:0043226 organelle
1.21 2.16e-11 GO:0043229 intracellular organelle
1.23 4.52e-11 GO:0043227 membrane-bounded organelle
1.70 4.90e-11 GO:0005739 mitochondrion
1.23 5.99e-11 GO:0043231 intracellular membrane-bounded organelle
1.82 1.38e-10 GO:0042995 cell projection
2.59 1.74e-10 GO:0044456 synapse part
1.75 6.92e-10 GO:0031090 organelle membrane
2.08 7.50e-09 GO:0043005 neuron projection
1.34 8.89e-08 GO:0071944 cell periphery
1.19 2.25e-07 GO:0016020 membrane
1.33 6.00e-07 GO:0005886 plasma membrane
1.90 1.11e-06 GO:0030054 cell junction
2.09 1.53e-06 GO:0005740 mitochondrial envelope
4.44 6.16e-06 GO:0070469 respiratory chain
1.47 7.24e-06 GO:0044459 plasma membrane part
2.06 8.29e-06 GO:0031966 mitochondrial membrane
1.90 9.38e-06 GO:0044429 mitochondrial part
1.82 1.40e-05 GO:0031975 envelope
4.65 1.61e-05 GO:0005746 mitochondrial respiratory chain
1.57 2.28e-05 GO:0000267 cell fraction
1.73 2.39e-05 GO:0031982 vesicle
2.16 2.75e-05 GO:0043025 neuronal cell body
2.01 2.81e-05 GO:0044463 cell projection part
1.78 5.98e-05 GO:0031967 organelle envelope
2.13 7.26e-05 GO:0005743 mitochondrial inner membrane
5.00 9.06e-05 GO:0005747 mitochondrial respiratory chain complex I
5.00 9.06e-05 GO:0030964 NADH dehydrogenase complex
5.00 9.06e-05 GO:0045271 respiratory chain complex I
1.71 1.22e-04 GO:0031410 cytoplasmic vesicle
2.22 1.35e-04 GO:0030424 axon
2.05 1.39e-04 GO:0044297 cell body
2.06 1.66e-04 GO:0019866 organelle inner membrane
3.12 1.79e-04 GO:0008021 synaptic vesicle
2.64 3.27e-04 GO:0030136 clathrin-coated vesicle
2.99 3.89e-04 GO:0044455 mitochondrial membrane part
1.57 6.27e-04 GO:0005626 insoluble fraction
1.17 9.11e-04 GO:0044425 membrane part
1.57 1.15e-03 GO:0005624 membrane fraction
2.36 1.79e-03 GO:0031252 cell leading edge
2.40 1.82e-03 GO:0030135 coated vesicle
1.72 2.02e-03 GO:0031988 membrane-bounded vesicle
1.74 2.19e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
2.55 2.28e-03 GO:0019717 synaptosome
2.39 2.70e-03 GO:0045211 postsynaptic membrane
1.22 3.27e-03 GO:0044446 intracellular organelle part
2.53 3.93e-03 GO:0033267 axon part
1.21 4.84e-03 GO:0044422 organelle part
1.77 5.74e-03 GO:0005768 endosome
1.55 7.45e-03 GO:0012505 endomembrane system
1.39 8.30e-03 GO:0005829 cytosol
1.46 2.49e-02 GO:0005794 Golgi apparatus
1.76 4.08e-02 GO:0005625 soluble fraction
1.85 4.24e-02 GO:0030425 dendrite
1.24 4.28e-02 GO:0043234 protein complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.34 1.11e-13 GO:0005515 protein binding
1.19 4.65e-13 GO:0005488 binding
2.35 3.16e-05 GO:0005083 small GTPase regulator activity
1.59 7.29e-05 GO:0005215 transporter activity
1.63 3.52e-04 GO:0030234 enzyme regulator activity
1.92 5.06e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.92 8.67e-04 GO:0030695 GTPase regulator activity
1.57 1.47e-03 GO:0022892 substrate-specific transporter activity
1.73 4.11e-03 GO:0019904 protein domain specific binding
1.58 4.22e-03 GO:0016301 kinase activity
1.51 8.88e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.51 1.62e-02 GO:0005516 calmodulin binding
1.58 1.66e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.64 2.00e-02 GO:0004672 protein kinase activity
1.51 2.15e-02 GO:0022857 transmembrane transporter activity
4.04 3.10e-02 GO:0019905 syntaxin binding
1.65 3.23e-02 GO:0008092 cytoskeletal protein binding
1.56 3.40e-02 GO:0015075 ion transmembrane transporter activity
1.17 3.59e-02 GO:0003824 catalytic activity
9.18 3.65e-02 GO:0001640 adenylate cyclase inhibiting metabotropic glutamate receptor activity
1.66 3.85e-02 GO:0008324 cation transmembrane transporter activity
3.67 4.04e-02 GO:0000149 SNARE binding
5.14 4.97e-02 GO:0035255 ionotropic glutamate receptor binding